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GitHub - NCBI-Hackathons/NCBIComputationalCookbook: Jupyter notebooks and other things to more effectively leverage computational resources at NCBI
Designing Educational Experiences with Jupyter Notebooks:

Overview:

Poor documentation leads to poor understanding of a software. Hence, we have designed a template Jupyter Notebook for more effective uses of resources via an interactive learning.

Strategy:



Goal:

To create a tutorial for teaching how to run a BLAST search from within BioPython and how to compare and identify unknown user provided biological sequences. Basic Local Alignment Search Tool (BLAST) is a tool used to align sequences and find regions of similarity between them. This Jupyter Notebook combines code and rich-text elements which allows the user to effectively learn, edit and run the notebook.

Example user persona:

Sarah, an undergrad student (major biology) is taking one unit of web-based bioinformatics, and has little programming experience. She has to solve the following assignment:

The goal is to determine if a recently-obtained genomic sequence from Drosophila yakuba (a relative of the model fruit fly Drosophila melanogaster) contains region(s) with sequence similarity to any known genes. The unknown sequence is an 11,000 base pair (bp) fragment of genomic DNA, and the objective of gene annotation is to find and precisely map the coding regions of any genes in this part of the genome.
genomics  jupyter  Education  Science 
20 hours ago by cnk
James Damore’s Google Memo Gets Science All Wrong | WIRED
the science in Damore’s memo is still very much in play, and his analysis of its implications is at best politically naive and at worst dangerous. The memo is a species of discourse peculiar to politically polarized times: cherry-picking scientific evidence to support a pre-existing point of view. It’s an exercise not in rational argument but in rhetorical point scoring. And a careful walk through the science proves it.
jamesdamore  googlememo  sexism  science  metascience  psychology  scienceculture  sciencecommunication 
21 hours ago by sampenrose
How to pedal perfectly, according to Wattbike | road.cc
Wattbike’s Pedalling Effectiveness Score is inspired by the index of force effectiveness (IFE) which is an existing way of expressing mechanical efficiency during pedalling. IFE compares the gross force – the total force applied to the pedal – and the net force – the component of force that is tangential to the chainset. In other words, it gives the proportion of force you put out that actually goes towards creating torque and turning the chainrings.

Pedalling Effectiveness Score is calculated from Wattbike’s 100Hz force data as you ride. After measuring your net force and predicting your gross force, the Pedal Effectiveness Score function displays a real-time pedal stroke graphic alongside a target score graphic, including a colour-coded breakdown for each leg. This information is intended to provide the basis for adjusting your pedal technique until you’re cycling efficiently.
cycling  physiology  science 
22 hours ago by juliusbeezer
James Damore’s Google Memo Gets Science All Wrong | WIRED
The problem is, the science in Damore’s memo is still very much in play, and his analysis of its implications is at best politically naive and at worst dangerous. The memo is a species of discourse peculiar to politically polarized times: cherry-picking scientific evidence to support a pre-existing point of view. It’s an exercise not in rational argument but in rhetorical point scoring. And a careful walk through the science proves it.
science  google  psychology  sexism  wired 
yesterday by cmananian
florenceest — Second Nature: A Gardener's Education (Unabridged)...
RT : Second Nature: A Gardener's Education (Unabridged) - Michael Pollan | Science |358045342
Science  from twitter
yesterday by heyyouapp
Le mystère de la petite fille et de ses muscles «aussi faibles que des nouilles» | Slate.fr
Dès sa naissance, en avril 2007, il apparaît que Gabriela «Gg» Woodward n'est pas une petite fille comme les autres.
science 
yesterday by caeypi

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