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aries1988 : dna   3

‘Daisy-chain’ gene drive vanishes after only a few generations | New Scientist
Each element contains one or more genes that contribute towards the whole gene drive. In Esvelt’s design, element A can only copy and paste itself if element B is present. Element B can only copy and paste itself if element C is present. And element C, crucially, cannot copy and paste itself at all – it can only spread by normal breeding, to half of offspring.

The idea is to release thousands of mosquitoes, say, carrying all three elements. When they mate with wild mosquitoes, all the offspring will inherit element A and B, but only half will inherit element C. In the following generations, element B will spread rapidly and A will spread even more rapidly, but C will gradually die out. Once it does, B will start to disappear, and finally A will too.
biology  engineering  explained  dna 
february 2018 by aries1988

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