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pierredv : disease   8

William Utermohlen | Issues in Science and Technology Oct 2018
In 1995 Utermohlen was diagnosed with Alzheimer’s disease (AD). Signs of his illness are retrospectively apparent in the work of the early 1990s, notably in the Conversation Pieces, which depict the warmth and happiness of his relationship with his wife, art historian Patricia Redmond, and his rich companionship with friends.
IssuesInScienceAndTechnology  art  painting  ageing  Alzheimers  health  disease 
october 2018 by pierredv
How statistical deception created the appearance that statins are safe and effective in primary and secondary prevention of cardiovascular disease: Expert Review of Clinical Pharmacology: Vol 8, No 2
David M Diamond & Uffe Ravnskov

Abstract: "We have provided a critical assessment of research on the reduction of cholesterol levels by statin treatment to reduce cardiovascular disease. Our opinion is that although statins are effective at reducing cholesterol levels, they have failed to substantially improve cardiovascular outcomes. We have described the deceptive approach statin advocates have deployed to create the appearance that cholesterol reduction results in an impressive reduction in cardiovascular disease outcomes through their use of a statistical tool called relative risk reduction (RRR), a method which amplifies the trivial beneficial effects of statins. We have also described how the directors of the clinical trials have succeeded in minimizing the significance of the numerous adverse effects of statin treatment."

Per, "According to Diamond and Ravnskov, statins produce a dramatic reduction in cholesterol levels, but they have "failed to substantially improve cardiovascular outcomes." They further state that the many studies touting the efficacy of statins have not only neglected to account for the numerous serious adverse side effects of the drugs, but supporters of statins have used what the authors refer to as "statistical deception" to make inflated claims about their effectiveness."
statins  ASCVD  disease  health  healthcare  statistics 
december 2017 by pierredv
Feeling lonely? You're not on your own | New Scientist issue 3134, 22 Jul 2017
"Anyone can feel lonely, even when surrounded by friends, and loneliness is on the up. How can we curb its devastating effect on people's mental and physical health?"

"Yet loneliness may have very little to do with being on our own, or having few friends, even if this is how it is often defined. “It’s not social isolation; it’s feeling socially isolated,” says Cacioppo ... Loneliness arises from a mismatch between expectations of our social interactions and the reality."

“Correcting for demographic factors, loneliness increases the odds of early mortality by 26 per cent,” says Cacioppo. “That’s about the same as living with chronic obesity.”

"If there’s one factor that stands out in alleviating loneliness, then it is the quality, rather than quantity of relationships. "

Robin Dunbar: “For you to live, survive, work and function well depends on you having a set of very intense close friendships, or family relationships. It turns out that this core group numbers about five close friends and family – and this is very consistent across primates, including humans.”
NewScientist  psychology  loneliness  feelings  emotion  disease  mortality 
december 2017 by pierredv
42nd St paradox: Cull the best to make things better - physics-math - 16 January 2014 - New Scientist
"According to the emerging science of networks, there are good reasons why some systems perform better in seemingly disadvantageous conditions." Dietrich Braess, late 60s: "while working on ways to find the optimal solution for traffic flow through a network of roads that he made a surprising discovery: adding an extra street to a simple network can actually increase overall travel times" Good road traffic example why Nash Equilibrium isn't optimal: "Suppose five drivers choose the 10-minute journey on the highway. The other five take the shorter route giving them a 5-minute commute. Now the average journey time is 7.5 minutes – the shortest possible average." Examples from other fields: basketball, electricity generation, wireless grids, food webs, metabolic pathways
Braess  Nash  nash.equilibrium  network  NewScientist  networking  network-analysis  traffic  disease  ** 
july 2014 by pierredv
Parasitology: The risks of global worming | The Economist
"Widespread use of anti-parasite drugs is reducing their value" "No one farmer is to blame. This is a tragedy of the commons, in which sensible individual decisions have led to a collective difficulty. But it might behove farmers to think more about how they use anti-worm drugs. If they do not, they may find that those drugs have become useless."
sheep  TheEconomist  commons  economics  disease 
july 2012 by pierredv
Genes, germs and the origins of politics - environment - 24 May 2011 - New Scientist
"A controversial new theory claims fear of infection makes the difference between democracy and dictatorship" Story about work of Randy Thornhill: "He says that the nature of the political system that holds sway in a particular country - whether it is a repressive dictatorship or a liberal democracy - may be determined in large part by a single factor: the prevalence of infectious disease." so-called parasite stress model
disease  politics  democracy  NewScientist 
june 2011 by pierredv
Mind Hacks: Questioning 'one in four'
What counts as being having a disease? It's not just a problem for psychological disorders. An extended discussion
depression  disease  psychology 
april 2010 by pierredv

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